ABSTRACT
@#Objective To explore the impact of different presentations on the image understanding of children with autism. Methods From November, 2016 to March, 2017, 30 pupils with autism aged seven to 14 years in the special education school were observed the understanding of picture, in term of characters, continuations and sequences, and their focus was recorded with the eye tracker. Results The comprehension score was the highest for the picture with cartoon characters, continuous and non-sequential (F=9.99, P<0.001). There was no correlation between the distribution of the focus and comprehension rate (r=0.27, P>0.05). Direct or indirect experience and omiting content did not impact the comprehension rate (t<1.522, P>0.05).Conclusion Compared with strange photos, images of fixed cartoon characters are more conducive to understand for children with autism. Disrupting the order of the picture and omitting some of the sequence do not affect the understanding, which is consistent with the theoretical hypothesis of central insufficiency.
ABSTRACT
Vanishing bile duct syndrome (VBDS) manifests as progressive destruction and disappearance of the intrahepatic bile duct caused by various factors and cholestasis. VBDS associated with drug-induced liver injury (D-VBDS) is an important etiology of VBDS, and immune disorder or immune imbalance may be the main pathogenesis. According to its clinical symptoms, serological markers, and course of the disease, D-VBDS is classified into major form and minor form, and its clinical features are based on various pathomorphological findings. Its prognosis is associated various factors including regeneration of bile duct cells, number of bile duct injuries, level and range of bile duct injury, bile duct proliferation, and compensatory shunt of bile duct branches. This disease has various clinical outcomes; most patients have good prognosis after drug withdrawal, and some patients may experience cholestatic cirrhosis, liver failure, and even death. Due to the clinical manifestation and biochemical changes are similar to the primary biliary cholangitis (PBC) and primary sclerosing cholangitis (PSC), it need to identify by clinical physician.
ABSTRACT
Objective To investigate the charactoristics of comprehension of words or phrases of nouns in chidren with autism. Meth-ods From November, 2014 to April, 2015, 43 children with autism and 10 with Down's syndrome aged 7-14 years accepting special educa-tion, and other 42 normal children aged 7-8 years were asked to identify the pictures according to the words, wearing Tobii Ⅱ Glasses to re-cord eyes movement. Results The incidence of right answer was more in the normal children than in the ones with autism or Down's syn-drome (χ2>5.647, P6.248, P7.15, P5.04, P<0.05). Conclusion Children with autism tend to focus on the words as the order of speech, but not the center word, which may influence the phrases understanding, and be influenced by the intuitive vision.